Not all sectors will benefit equally from the 2025 structural shifts. Here’s where capital is flowing—and where it’s retreating.
In 2026
Gaining Momentum
AI Agents & Automation
- Workflow integration accelerating
- Enterprise adoption surge
- Examples: n8n, LangChain, Decagon
Vertical AI
- Healthcare, Legal, Finance
- Domain expertise = moat
- Examples: OpenEvidence, Abridge
Defense Tech
- $1T+ budget tailwind
- Geopolitical urgency
- Examples: Anduril, Castellion
AI Infrastructure
- Compute demand surge
- Model serving at scale
- Examples: Fireworks AI, Modal
Facing Headwinds
Horizontal AI/SaaS
- Rapid commoditization
- Race to bottom pricing
- Margin compression
Climate Tech
- Long development cycles
- LP patience wearing thin
- Liquidity mismatch
Pure Crypto
- Post-2022 caution lingers
- Regulatory uncertainty
- Selective opportunities
Consumer Apps
- Enterprise focus dominating
- CAC/LTV challenges
- B2B preferred
The Pattern
- AI-native wins
- Vertical beats horizontal
- Fast cycles required
- Long-cycle = LP risk
- B2C headwinds
This is part of a comprehensive analysis. Read the full analysis on The Business Engineer.









